Tomohiko Ishihara Selected Research

U12 small nuclear RNA

2/2014	Minor splicing pathway is not minor any more: implications for the pathogenesis of motor neuron diseases.
10/2013	Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.

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Tomohiko Ishihara Research Topics

Disease

9	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 10/2013
2	Motor Neuron Disease (Primary Lateral Sclerosis) 02/2014 - 01/2014
2	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 11/2010 - 07/2010
1	Amyloidosis 05/2022
1	Atrophy 10/2019
1	Frontotemporal Dementia (Semantic Dementia) 01/2018
1	Posterior Leukoencephalopathy Syndrome 02/2017
1	Eclampsia 02/2017
1	Hypertension (High Blood Pressure) 02/2017
1	Renal Insufficiency (Renal Failure) 02/2017
1	Disease Progression 02/2017
1	Hyponatremia 01/2017
1	Glycogen Storage Disease Type II (Pompe's Disease) 01/2016
1	Dementia (Dementias) 01/2015
1	Glioma (Gliomas) 01/2015
1	Liver Diseases (Liver Disease) 01/2015
1	Neurosyphilis (General Paresis of the Insane) 01/2015
1	Multiple Sclerosis 08/2013
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 07/2010
1	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2010
1	Corticobasal Degeneration 07/2010
1	Nonaka type Distal myopathy 04/2008
1	Tremor (Tremors) 04/2008
1	Parkinsonian Disorders (Parkinsonism) 04/2008

Drug/Important Bio-Agent (IBA)

6	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2021 - 11/2010
2	mecobalamin (methylcobalamin)IBA 01/2022 - 12/2018
2	Proteins (Proteins, Gene)FDA Link 11/2019 - 07/2010
2	U12 small nuclear RNAIBA 02/2014 - 10/2013
1	patisiranIBA 05/2022
1	Eosine Yellowish-(YS) (Eosin)IBA 10/2019
1	Hematoxylin (Haematoxylon)IBA 10/2019
1	SodiumIBA 01/2017
1	AcidsIBA 01/2016
1	alpha-Glucosidases (Acid Maltase)IBA 01/2016
1	Erythromycin (Erycette)FDA LinkGeneric 01/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2015
1	AntibodiesIBA 01/2015
1	Penicillins (Penicillin)FDA Link 01/2015
1	RNA (Ribonucleic Acid)IBA 01/2014
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2014
1	Fingolimod Hydrochloride (FTY720)FDA Link 08/2013
1	UbiquitinIBA 11/2010
1	Levodopa (L Dopa)FDA LinkGeneric 04/2008

Therapy/Procedure

4	Therapeutics 05/2022 - 08/2013
1	Tracheostomy 01/2022
1	Blood Transfusion (Blood Transfusions) 02/2017